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KMID : 0376619950200010064
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Seoul Journal of Psychiatry
1995 Volume.20 No. 1 p.64 ~ p.72
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A Case of Alprazolam Induced Mania in a Patient with Anxiety Disorder
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Abstract
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A patient treated with alprazolam for anxiety disorder developed a manic episode. These symptoms remitted upon discontinuation of treatment.
Subsequent administration of an equivalent dosage of lorazepam did not induce manic symptoms.
The clinical and theoretical implications of these findings are discussed in relation to the possible mechanisms of action of alprazolam. The authors caution that treatment with alprazolam may be complicated by the induction of mania.
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